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Technology Access Program for Custom PhIP-Seq Libraries

Our new Technology Access Program for custom PhIP-Seq libraries enables you to conduct epitope-level antibody discovery and profiling using a PhIP-Seq library tailored to your specific needs.

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Custom PhIP-Seq Libraries Tailored to Your Specific Research

We are now offering custom PhIP-Seq libraries through a Technology Access Program.

PhIP-Seq (Phage ImmunoPrecipitation Sequencing) is a powerful method of highly multiplexed analysis that combines next-gen proteomics with high-throughput DNA sequencing. It offers detailed insights into antigen-antibody interactions and immune responses across a wide range of research applications.

Our new Technology Access Program enables you to conduct epitope level antibody discovery and profiling using a PhIP-Seq library tailored to your specific needs. Library design can be specific to a particular disease, autoimmune disorder, allergy panel, or any other application. In addition, you can add new content to any of our existing PhIP-Seq library products using a spike-in approach that enables access to the extended library at a lower cost.

As part of the custom PhIP-Seq TAP CDI Labs Canada will:

  • Collaborate on the design of the library to help ensure that your research goals are achieved efficiently and cost-effectively.
  • Run the samples at our Toronto facility which is solely dedicated to PhIP-Seq services.
  • Provide dedicated data analysis services to help translate raw data into meaningful results that will accelerate your research goals.

CDI Labs PhIP-Seq Services

HuScan

HuScan enables simultaneous epitope-level autoantibody profiling versus an entire NCBI human proteome (48,921 proteins and isoforms) via phage-display and immunoprecipitation sequencing.

VirScan

VirScan allows researchers to determine what antibodies were created by an individual’s unique history of viral exposures. VirScan enables simultaneous epitope-level autoantibody profiling versus most vertebrate viruses.

MouseScan

MouseScan enables simultaneous epitope-level autoantibody profiling versus an entire GRCm38.p5 mouse proteome (50,135 proteins and isoforms) via phage immunoprecipitation sequencing.

Benefits of PhIP-Seq

    1. High-throughput and Comprehensive

  • Large-scale Profiling: Allows for the simultaneous analysis of hundreds of thousands of peptides or antigens, providing a broad view of the immune response against a wide array of potential targets.
  • Detailed Antibody Mapping: Can identify specific peptide or protein sequences recognized by antibodies, offering detailed insights into antigenic epitopes.

    • 2. Enhanced Sensitivity and Specificity

  • Detects Low-Abundance Targets: Capable of detecting antibodies against low-abundance or rare antigens, which might be missed by other methods.
  • High Resolution: Provides precise information about the exact peptide or protein sequences that antibodies bind to, aiding in the identification of specific epitopes.

    • 3. Customizable

  • Flexible Design: The peptide libraries can be customized to target specific proteins or epitopes of interest, making it adaptable to different research needs.

    • 4. High Reproducibility

  • Consistent Results: Offers reliable and reproducible results due to the use of standardized phage libraries and sequencing technologies.

    • 5. Data Integration and Analysis

  • Rich Data Output: Enables detailed bioinformatics analysis to identify patterns and correlations in antibody responses.

Why Work with CDI Labs?

CDI Labs Canada is exclusively focused on providing the highest quality PhIP-seq assay services available today. Let us manage the complex laboratory workflows so you can focus on moving your research forward with best-in-class data quality.

Choosing CDI Labs as your partner means aligning with a leader in cutting-edge proteomic services with over 15 years of experience. Our customized solutions are tailored to meet the specific needs of your research or clinical applications, whether you're exploring novel biomarkers, profiling viral exposures, or developing targeted therapies. By working with us, you gain access to a team of dedicated scientists, robust data, and proven methodologies that can drive your projects forward, ensuring reliable, reproducible, and meaningful results.

Expert Personnel

Our labs are staffed by experienced scientists with specialized training in using sophisticated equipment to run complex assay services.

Innovative Techniques and Protocols

Our labs employ validated workflows which have been optimized over the last 5 years. Laboratory workflows and NGS techniques are optimized to provide superior data quality while eliminating false positives.

Data Analysis and Interpretation

We offer best-in-class data analysis pipelines and a highly experienced bioinformatics team that enable customers to translate raw data into meaningful insights.

Quality Control

We apply stringent quality control processes to ensure the accuracy, reliability, and reproducibility of all results.

Collaborative Approach

We are committed to work closely with researchers, offering support and guidance throughout the project.

Custom PhIP-Seq Contact Form

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